GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs2905426 | 1 | rs2315281 | chr19:19480099 | YJEFN3 | chr19:19639720-19648393:+ | 0.23 | 4.58 | 6.27E-6 | Schizophrenia |
| BLCA | cis | rs2318131 | 1 | rs2318131 | chr2:237933966 | IQCA1 | chr2:237232794-237416092:- | -0.23 | -3.86 | 0.000131 | Motion sickness |
| BLCA | cis | rs6805251 | 1 | rs2319399 | chr3:119636207 | KTELC1 | chr3:119187785-119213552:+ | -0.22 | -3.83 | 0.000151 | HDL cholesterol |
| BLCA | cis | rs1577917 | 1 | rs2324843 | chr6:86617501 | SNHG5 | chr6:86386726-86388451:- | -0.54 | -9.46 | 3.23E-19 | Response to antipsychotic treatment |
| BLCA | cis | rs454422 | 1 | rs2326680 | chr20:5942955 | MCM8 | chr20:5931298-5975829:+ | -0.21 | -4.43 | 1.26E-5 | HIV-1 viral setpoint |
| BLCA | cis | rs2340727 | 1 | rs2340727 | chr1:161946727 | RPL31P11 | chr1:161653497-161655042:- | 0.3 | 3.89 | 0.000116 | Hematology traits |
| BLCA | cis | rs7714584 | 1 | rs2344180 | chr5:150267357 | LOC134466 | chr5:150310000-150326146:- | 0.47 | 6.15 | 1.94E-9 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs2344181 | chr5:150262574 | LOC134466 | chr5:150310000-150326146:- | 0.46 | 6.12 | 2.36E-9 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs2345001 | chr5:150266518 | LOC134466 | chr5:150310000-150326146:- | 0.47 | 6.24 | 1.17E-9 | Crohn's disease |
| BLCA | cis | rs2028299 | 1 | rs2351706 | chr15:90384115 | AP3S2 | chr15:90373832-90456222:- | -0.7 | -10.62 | 2.88E-23 | Type 2 diabetes |
| BLCA | cis | rs2028299 | 1 | rs2351707 | chr15:90384045 | AP3S2 | chr15:90373832-90456222:- | -0.7 | -10.67 | 1.87E-23 | Type 2 diabetes |
| BLCA | cis | rs11723261 | 1 | rs2353605 | chr4:219538 | ZNF718 | chr4:53272-156488:+ | 0.29 | 4.06 | 6.07E-5 | Immune response to smallpox vaccine (IL-6) |
| BLCA | cis | rs4660306 | 1 | rs2356559 | chr1:45981512 | CCDC163P | chr1:45960581-45965646:- | -0.76 | -15.61 | 7.05E-43 | Homocysteine levels |
| BLCA | cis | rs4660306 | 1 | rs2356561 | chr1:45980862 | CCDC163P | chr1:45960581-45965646:- | -0.73 | -14.77 | 2.1E-39 | Homocysteine levels |
| BLCA | cis | rs2239557 | 1 | rs2358628 | chr14:74631757 | LIN52 | chr14:74551656-74667117:+ | -0.36 | -8.05 | 1.06E-14 | Common traits (Other) |